Definition of chemica penetration



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Collins english language Dictionary - full-blown & Unabridged 2012 integer Edition © William writer Sons & Co.
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Penetrating | Define Penetrating at Dictionary.com


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, measures the concentration or perception of a substance “through the skin barrier and into the skin” (OECD, 2004a). Dermal entry studies are conducted to regulate how much of a material penetrates the skin, and thereby whether it has the potential to be absorbed into the general circulation. Dermal onslaught is reasoned to occur by passive diffusion; however, biotransformation of the test substance within the deeper viable regions of the connective tissue (metabolism) prior to systemic absorption can occur (OECD, 2004a)., on the other hand, is conducted to measure the local and/or general personal property of a chemic following dermal exposure.
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